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Differential expression of AMPA-type glutamate receptor subunits during development of the chick optic tectum BJMBR
Batista,S.S.; Pires,R.S.; Britto,L.R.G..
Glutamate receptors have been often associated with developmental processes. We used immunohistochemical techniques to evaluate the expression of the AMPA-type glutamate receptor (GluR) subunits in the chick optic tectum (TeO). Chick embryos from the 5th through the 20th embryonic day (E5-E20) and one-day-old (P1) chicks were used. The three types of immunoreactivity evaluated (GluR1, GluR2/3, and GluR4) had different temporal and spatial expression patterns in the several layers of the TeO. The GluR1 subunit first appeared as moderate staining on E7 and then increased on E9. The mature GluR1 pattern included intense staining only in layer 5 of the TeO. The GluR2/3 subunits presented low expression on E5, which became intense on E7. The staining for...
Tipo: Info:eu-repo/semantics/other Palavras-chave: AMPA; Development; Glutamate receptors; Neurotransmitters; Receptor subunits; Visual system.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800015
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Distribution of the a2, a3, and a5 nicotinic acetylcholine receptor subunits in the chick brain BJMBR
Torrão,A.S.; Lindstrom,J.M.; Britto,L.R.G..
Nicotinic acetylcholine receptors (nAChRs) are ionotropic receptors comprised of <FONT FACE="Symbol">a</font> and ß subunits. These receptors are widely distributed in the central nervous system, and previous studies have revealed specific patterns of localization for some nAChR subunits in the vertebrate brain. In the present study we used immunohistochemical methods and monoclonal antibodies to localize the <FONT FACE="Symbol">a</font>2, <FONT FACE="Symbol">a</font>3, and <FONT FACE="Symbol">a</font>5 nAChR subunits in the chick mesencephalon and diencephalon. We observed a differential distribution of these three subunits in the chick brain, and showed that the somata and neuropil of many central...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholinergic system; Neurotransmitters; Receptors; Receptor subunits.
Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997001000011
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